文献类型：期刊文献

英文题名：Catalyst-Controlled Selectivity Switch in Three-Component Reaction: An NHC-Catalyzed Strategy for the Synthesis of delta-Lactone-Fused Spirobenzofuran-3-ones

作者：Wang, Zhanyong[1];Yang, Ting[2];Liu, Dongfang[3];Chen, Rongxiang[1];Wang, Nan[1];Liu, Hong[1];Li, Jiarong[1];Wang, Kaikai[1];Liu, Hongxin[4,5]

通讯作者：Wang, KK[1];Liu, HX[2];Liu, HX[3]

机构：[1]Xinxiang Univ, Sch Pharm, Xinxiang 453003, Henan, Peoples R China;[2]Xinxiang Univ, Nursing Coll, Xinxiang 453003, Henan, Peoples R China;[3]Xinxiang Runyu Mat Co Ltd, Xinxiang 453003, Henan, Peoples R China;[4]Wenzhou Univ, Coll Chem & Mat Engn, Wenzhou 325035, Peoples R China;[5]Wenzhou Univ, Inst New Mat & Ind Technol, Wenzhou 325035, Peoples R China

第一机构：新乡学院

通讯机构：[1]corresponding author), Xinxiang Univ, Sch Pharm, Xinxiang 453003, Henan, Peoples R China;[2]corresponding author), Wenzhou Univ, Coll Chem & Mat Engn, Wenzhou 325035, Peoples R China;[3]corresponding author), Wenzhou Univ, Inst New Mat & Ind Technol, Wenzhou 325035, Peoples R China.|[11071]新乡学院;

年份：2022

卷号：27

期号：18

外文期刊名：MOLECULES

收录：;Scopus(收录号：2-s2.0-85138343200);WOS:【SCI-EXPANDED(收录号:WOS:000857757000001)】；

基金：Financial support was received from the NSFC (21801214), the Program for Youth Backbone Teacher Training in the University of Henan Province (2021GGJS163), The Higher Education Institution Key Research Project Plan of Henan Province of China (22B150015), the Natural Science Foundation of Henan Province (202300410016), the Foundation of 2021 Wenzhou Association for Science and Technology Service innovation project (kjfw35) and the Foundation of Zhejiang Educational Committee (Y201839490).

语种：英文

外文关键词：N-heterocyclic carbenes; alpha; beta-unsaturated acylazoliums; Spirobenzofuran-3-one; three-component reaction; delta-Lactones

摘要：An efficient, three-component reaction of aldehydes and benzofuran-3-ones was developed. This process provides a new approach for the preparation of synthetically and biologically important spirobenzofuran-3-one derivatives with moderate-to-good yields under mild conditions. A switch of intramolecular to intermolecular domino Michael-aldol-lactonization leading to differential product formation was achieved by different NHCs catalysis.