文献类型：期刊文献

英文题名：Amino Acid Detection with Bare Eyes Based on Two Different Concentrations of Iodides as Sensor Receptors

作者：Li, Li[1];Gu, Xuewei[2];Wang, Junli[1];Chen, Zhengbo[3]

第一作者：李丽

通讯作者：Li, L[1];Wang, JL[1]

机构：[1]Xinxiang Univ, Sch Chem & Mat Engn, Xinxiang 453003, Henan, Peoples R China;[2]Anhui Normal Univ, Coll Chem & Mat Sci, Wuhu 241002, Peoples R China;[3]Capital Normal Univ, Dept Chem, Beijing 100048, Peoples R China

第一机构：新乡学院

通讯机构：[1]corresponding author), Xinxiang Univ, Sch Chem & Mat Engn, Xinxiang 453003, Henan, Peoples R China.|[11071]新乡学院;

年份：2021

卷号：14

期号：9

起止页码：1927-1935

外文期刊名：FOOD ANALYTICAL METHODS

收录：;EI(收录号：20211610234015);Scopus(收录号：2-s2.0-85104295103);WOS:【SCI-EXPANDED(收录号:WOS:000640132500001)】；

基金：All authors gratefully acknowledge the Natural Science Foundation of China (Grant No. 21801215).

语种：英文

外文关键词：Colorimetric; Iodide; Sensing array; Sulfur-containing amino acid; Linear discriminant analysis

摘要：Sulfur containing amino acids play an important role in human physiology, and different levels of amino acids in organisms can cause serious health problems. Herein, we have developed a core-shell Cu@Au nanoparticles (Cu@AuNPs)-based powerful colorimetric sensing array for differentiation of containing amino acid. The sensors consist of two different concentrations of iodides (1.5 mu M KI and 0.5 mu M NaI) as sensor receptors and Cu@AuNPs as signal readout. With the amino acids, iodide can easily get access to the Cu@AuNP surface, inducing a visual color variation (gray -> red) of the Cu@AuNP solution by means of changing the Cu@AuNP clusters to separated, spherical-like, and larger ones. While without the target amino acids, various amino acids show differential binding interactions toward Cu@AuNPs via gold-sulfur bonds. So, the transformation is blocked to diverse degrees due to a competition adsorption between amino acids and iodides to the Cu@AuNPs. Consequently, varying levels of Cu@AuNP transformation are relevant with different amino acids and iodides, generating distinct colorimetric reaction modes, which are characteristic for each amino acid and can be quantitatively detected by linear discriminant analysis (LDA). Four target amino acids have been successfully identified at the 20 nM level. Additionally, the sensing system shows outstanding potential for analysis of complex samples.