文献类型：期刊文献

英文题名：A Coumarin-Based Fluorescence Probe for Selective Recognition of Cu2+ Ions and Live Cell Imaging

作者：He, Guangjie[1]; Ma, Nana[2]; Li, Linlin[1]; Xie, Chenyan[1]; Yang, Linlin[1]; Xu, Jinhe[1]; Wang, Junli[3]

第一作者：He, Guangjie

通讯作者：He, Guangjie

机构：[1] Xinxiang Key Laboratory of Forensic Science Evidence, School of Forensic Medicine, Xinxiang Medical University, Jinsui Road No. 601, Xinxiang Henan Province, 453003, China; [2] School of Chemistry and Chemical Engineering, Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, Henan Key Laboratory of Boron Chemistry and Advanced Energy Materials, Henan Normal University, East of Construction Road No. 46, Xinxiang Henan Province, 453007, China; [3] College of Chemistry and Chemical Engineering, Xinxiang University, Jinsui Road No. 191, Xinxiang Henan Province, 453003, China

第一机构：Xinxiang Key Laboratory of Forensic Science Evidence, School of Forensic Medicine, Xinxiang Medical University, Jinsui Road No. 601, Xinxiang Henan Province, 453003, China

年份：2019

卷号：2019

外文期刊名：Journal of Sensors

收录：EI(收录号：20194707711376);Scopus(收录号：2-s2.0-85075103275)

语种：英文

外文关键词：Absorption spectroscopy - Emission spectroscopy - Fluorescence - Metal ions - Metals - Probes - Ultraviolet spectroscopy

摘要：A new fluorescence probe L was rationally designed and synthesized for the recognition of Cu2+ ions by the combination of coumarin hydrazide and 2-Acetylpyrazine. The photochemical properties and selectivity of L for Cu2+ ions in a CH3CN/HEPES (3: 2, v/v) buffer were investigated by UV-vis absorption and fluorescence emission spectra. A highly selective and sensitive response of L for Cu2+ ions over other competing metal ions was observed with limit of detection in 3 μM. The coordination stoichiometry of L to Cu2+ ions was determined to be 1: 1 by the UV-vis absorption spectrum, the fluorescence titrations, and density functional theory (DFT) calculations. Moreover, L was applied successfully for recognition of intracellular Cu2+ ions in living cells. ? 2019 Guangjie He et al.