文献类型：期刊文献

英文题名：1,3-Dipolar cycloaddition of isatinN,N '-cyclic azomethine imines with alpha,beta-unsaturated aldehydes catalyzed by DBU in water

作者：Wang, Zhan-Yong[1];Yang, Ting[2];Chen, Rongxiang[1];Ma, Xueji[1];Liu, Huan[1];Wang, Kai-Kai[1]

第一作者：王占勇

通讯作者：Wang, KK[1]

机构：[1]Xinxiang Univ, Coll Chem & Chem Engn, Xinxiang 453003, Henan, Peoples R China;[2]Xinxiang Univ, Med Coll, Xinxiang 453003, Henan, Peoples R China

第一机构：新乡学院化学化工学院

通讯机构：[1]corresponding author), Xinxiang Univ, Coll Chem & Chem Engn, Xinxiang 453003, Henan, Peoples R China.|[110713]新乡学院化学化工学院;[11071]新乡学院;

年份：2020

卷号：10

期号：41

起止页码：24288-24292

外文期刊名：RSC ADVANCES

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000544898700017)】；

基金：We gratefully acknowledge the National Natural Science Foundation of China (21801214, 21702176), Foundation of University Student Innovation Program (201911071001, S201911071007).

语种：英文

摘要：A simple and green procedure was established by [3 + 3] cycloaddition reaction of isatin derived cyclic imine 1,3-dipoles with alpha,beta-unsaturated aldehydes, giving the desired spiro heterocyclic oxindoles with aza-quaternary centers in good yields and diastereoselectivities. It should be noted that water can be employed as a suitable solvent for the improvement of diastereoselectivity.