文献类型：期刊文献

英文题名：High throughput sensing of multiple amino acids with differential pulse voltammetry measurement

作者：Li, Li[1];Chen, Leishan[1];Chen, Zhengbo[2]

第一作者：李丽

通讯作者：Chen, LS[1];Chen, ZB[2]

机构：[1]Xinxiang Univ, Sch Chem & Mat Engn, Xinxiang 453003, Henan, Peoples R China;[2]Capital Normal Univ, Dept Chem, Beijing 100048, Peoples R China

第一机构：新乡学院

通讯机构：[1]corresponding author), Xinxiang Univ, Sch Chem & Mat Engn, Xinxiang 453003, Henan, Peoples R China;[2]corresponding author), Capital Normal Univ, Dept Chem, Beijing 100048, Peoples R China.|[11071]新乡学院;

年份：2022

卷号：647

外文期刊名：ANALYTICAL BIOCHEMISTRY

收录：;EI(收录号：20221712012629);Scopus(收录号：2-s2.0-85128570554);WOS:【SCI-EXPANDED(收录号:WOS:000830644500009)】；

基金：This study was supported by the Key Scientific and Technological Project of Henan Province (Grant No. 222102310380).

语种：英文

外文关键词：Sensor array; Electrochemical; poly(3,4-ethylenedioxythiophene); Linear discriminant analysis; Amino acids

摘要：The content of amino acids in human body is closely related to human health and plays an important role in physiological regulation and medical function. In order to recognize a variety of amino acids, an electrochemical sensor array based on poly(3, 4-ethylenedioxythiophene) (PEDOT) electrode was established by using two kinds of electropolymerizers, i.e., citrate and the mixture of citrate and potassium nitrate as sensing elements. Different electropolymerizers lead result in different amount of negative charge on PEDOT electrode, which leads to different adsorption capacity for positive charge amino acids and different repulsion capacity for negative charge amino acids, bringing about obvious changes in differential pulse voltammetry (DPV) current. The five amino acids were accurately identified by linear discriminant analysis (LDA), and the electrochemical sensor array was successfully applied in the differential detection of amino acids in milk.