文献类型：期刊文献

英文题名：Fabrication of protein-coated CdS nanocrystals via microwave-assisted hydrothermal method

作者：Xing, Ruimin[1];Guo, Jianhui[1];Miao, Chaolin[2];Liu, Shanhu[1];Pan, Hongcheng[3]

第一作者：Xing, Ruimin

通讯作者：Liu, SH[1]

机构：[1]Henan Univ, Inst Environm & Analyt Sci, Coll Chem & Chem Engn, Kaifeng 475001, Peoples R China;[2]Xinxiang Univ, Dept Chem & Chem Engn, Xinxiang 453003, Peoples R China;[3]Guilin Univ Technol, Coll Chem & Bioengn, Guilin 541004, Peoples R China

第一机构：Henan Univ, Inst Environm & Analyt Sci, Coll Chem & Chem Engn, Kaifeng 475001, Peoples R China

通讯机构：[1]corresponding author), Henan Univ, Inst Environm & Analyt Sci, Coll Chem & Chem Engn, Kaifeng 475001, Peoples R China.

年份：2014

卷号：9

期号：6

起止页码：582-587

外文期刊名：JOURNAL OF EXPERIMENTAL NANOSCIENCE

收录：;EI(收录号：20142017714204);Scopus(收录号：2-s2.0-84899795531);WOS:【SCI-EXPANDED(收录号:WOS:000335214800006)】；

基金：This work was financially supported by National Natural Science Foundation of China (21101056, 21105021 and 20905016), Educational Commission of Henan Province of China (2011A150005) and Guangxi Natural Science Foundation (0991082). We also thank the Foundation of State Key Laboratory of Coordination Chemistry of China (No. 2010-20).

语种：英文

外文关键词：cadmium sulphide; nanocrystal; biocompatible; hydrothermal

摘要：CdS nanocrystals coated with protein were synthesised in the aqueous solution of bovine serum albumin protein by a rapid microwave-assisted hydrothermal method. Transmission electron microscopy, X-ray powder diffraction, Fourier transform infrared spectroscopy, thermogravimetric analysis (TGA) and cell cytotoxicity were used to characterise the morphology, composition and properties of the nanocrystals. The results indicate that the as-prepared CdS nanocrystals were wrapped up with the protein. The cytotoxicity profile on the human cervical cancer cell line HeLa shows that the potential cellular toxicity of the nanocrystals is efficiently prevented due to the presence of protein coating, which may offer the possibility of applications in biomedical research.