文献类型：期刊文献

中文题名：地黄中环烯醚萜苷的生物合成研究进展

英文题名：Research advances of iridoids glycosides biosynthesis in Rehmannia glutinosa

作者：徐小博[1];徐萍[1];夏然[2];任敏[1]

第一作者：徐小博

机构：[1]新乡学院生命科学技术学院;[2]新乡学院化学化工学院

第一机构：新乡学院生命科学技术学院

年份：2018

卷号：28

期号：5

起止页码：508-512

中文期刊名：生物技术

外文期刊名：Biotechnology

收录：CSTPCD

基金：新乡学院博士科研启动项目("地黄环烯醚萜生物合成途径及调控研究";No.1366020055);国家自然科学基金("碳自由基参与的基于嘌呤C-H键官能化构建烷基/芳基嘌呤核苷(酸)的研究";No.21602189)

语种：中文

中文关键词：环烯醚萜苷;生物合成途径;10-氧香叶醛;相关酶;调控

外文关键词：iridoids glycosides;biosynthetic pathway;10 - oxygeranial;related enzymes;regulation

摘要：环烯醚萜苷是传统名贵药材地黄中的主要活性成分,具有重要的药理活性。环烯醚萜苷的生物合成在长春花中研究最早也最成熟,而地黄中的环烯醚萜结构与长春花等植物有所不同,近十年来地黄中环烯醚萜苷的生物合成研究逐渐增多。阐明地黄中环烯醚萜苷的生物合成途径具有重要意义。该文对地黄中环烯醚萜苷的生物合成途径、关键酶和基因及其合成调控的最新研究进展进行综述,以期为深入研究提供参考。
Iridoids glycosides, the main active components of Chinese traditional valuable medicinal herb Rehmannia glutinosa, have important pharmacological activities. The biosynthesis of iridoid glycosides researches was first carried on Catharanthus roseus,and many achievements was obtained. However, the structures of iridoid glycosides in Rehmannia glutinosa are different from those in Catharanthus roseus and other plants, and the biosynthesis of iridoid glycosides in Rehmannia glutinosa has gradually increased in the past decade. To clarify the biosynthetic pathway of iridoid glycosides in Rehmannia glutinosa has important theoretical significance and broad application prospects. This paper reviewed the research progress on the biosynthetic pathway of iridoids, key enzymes and genes in R. glutinosa and their regulation. We expect this review could provide reference for further studies on iridoids biosynthesis.