文献类型：期刊文献

英文题名：Determination of Benzimidazole Residues in Edible Animal Food by Polymer Monolith Microextraction Combined with Liquid Chromatography-Mass Spectrometry

作者：Hu, Xi-Zhou[1,2];Wang, Jian-Xing[3];Feng, Yu-Qi[1]

第一作者：Hu, Xi-Zhou

通讯作者：Feng, YQ[1]

机构：[1]Wuhan Univ, Key Lab Analyt Chem Biol & Med, Minist Educ, Dept Chem, Wuhan 430072, Peoples R China;[2]Hubei Acad Agr Sci, Ctr Agr Testing S&T Informat, Wuhan 430064, Peoples R China;[3]Xinxiang Univ, Coll Chem & Chem Engn, Xinxiang 453000, Peoples R China

第一机构：Wuhan Univ, Key Lab Analyt Chem Biol & Med, Minist Educ, Dept Chem, Wuhan 430072, Peoples R China

通讯机构：[1]corresponding author), Wuhan Univ, Key Lab Analyt Chem Biol & Med, Minist Educ, Dept Chem, Wuhan 430072, Peoples R China.

年份：2010

卷号：58

期号：1

起止页码：112-119

外文期刊名：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

收录：;Scopus(收录号：2-s2.0-75249107154);WOS:【SCI-EXPANDED(收录号:WOS:000273268100015)】；

基金：This work was partly supported by the National Science Fund for Distinguished Young Scholars (No. 20625516), the Science Fund for Creative Research Groups (No. 20621502), NSFC, and the National Key Technologies R&D Program (2006BAF07B03).

语种：英文

外文关键词：Benzimidazole; liquid chromatography-electrospray ionization mass spectrometry; polymer monolith microextraction; animal food

摘要：A sensitive method has been developed for the simultaneous determination of 10 benzimidazole residues and some of their metabolites in egg, milk, chicken, and pork. This method is based on the combination of polymer monolith microextraction (PMME) technique with liquid chromatography and electrospray ionization mass spectrometry (LC-ESI/MS). The extraction was performed with a poly(methacrylic acid-co-ethylene glycol dimethacrylate) (MAA-co-EGDMA) monolithic capillary column. Under the optimized extraction conditions, good extraction efficiencies for the targets were obtained with no matrix interference in the subsequent detection. The LODs (S/N = 3) for 10 benzimidazoles were found to be 0.56-2.76 ng g(-1) in egg, 0.50-1.41 ng mL(-1) in milk, 0.09-0.28 ng g(-1) in chicken, and 0.08-0.15 ng g(-1) in pork. The recoveries in egg, milk, chicken, and pork matrices ranged from 75.2 to 116.8% spiked at different levels with analytes, with RSDs of <13.7%. The method was later successfully applied for the determination of primary and metabolite residues in eggs after oral administration of albendazole to hens.