文献类型：会议论文

英文题名：Synthesis and Self-assembly Behavior of Chiral Amphiphilic Diblock Copolymers Bearing L-phenylalanine

作者：Zhou, Yong[1];Liu, Bing[1]

通讯作者：Zhou, Y[1]

机构：[1]Xinxiang Univ, Coll Chem & Chem Engn, Xinxiang 453003, Henan, Peoples R China

第一机构：新乡学院化学化工学院

通讯机构：[1]corresponding author), Xinxiang Univ, Coll Chem & Chem Engn, Xinxiang 453003, Henan, Peoples R China.|[110713]新乡学院化学化工学院;[11071]新乡学院;

会议论文集：International Conference on Smart Materials and Nanotechnology in Engineering (SMNE 2011)

会议日期：SEP 17-18, 2011

会议地点：Wuhan, PEOPLES R CHINA

语种：英文

外文关键词："Click" reaction; amphiphilic block copolymer; chiral micelles

摘要：Novel chiral amphiphilic diblock copolymers bearing L-phenylalanine was synthesized using a "click" reaction of N3-L-phenylalanine and MPEO-b-PGPE. The structure and composition of copolymers were characterized by 1H-NMR and elemental analysis. Additionally, the self-assembly behavior of these chiral copolymers was investigated in sodium dihydrogen phosphate buffer (pH 4.5): the CMC of copolymer MPEO-b-PGTP determined by the measurement of surface tension was 2.1 mg/mL; the size and morphology of the micelles were studied using TEM; the specific optical rotation ([alpha]25D) of the micellar solutions was also measured; the result indicated that the copolymers can form chiral micelles in sodium dihydrogen phosphate buffer (pH = 4.5).