文献类型：期刊文献

英文题名：Experimental study on improvement of freeze-drying process for porcine aorta

作者：Gui, Chao[1,2];Tao, Leren[1,3];Zhang, Yaqi[1]

第一作者：Gui, Chao;桂超

通讯作者：Tao, LR[1]

机构：[1]Univ Shanghai Sci & Technol, Sch Energy & Power Engn, 516 Jungong Rd, Shanghai 200093, Peoples R China;[2]Xinxiang Univ, Sch Civil Engn & Architecture, Xinxiang, Henan, Peoples R China;[3]Univ Shanghai Sci & Technol, Shanghai Key Lab Multiphase Flow & Heat Transfer, Shanghai, Peoples R China

第一机构：Univ Shanghai Sci & Technol, Sch Energy & Power Engn, 516 Jungong Rd, Shanghai 200093, Peoples R China

通讯机构：[1]corresponding author), Univ Shanghai Sci & Technol, Sch Energy & Power Engn, 516 Jungong Rd, Shanghai 200093, Peoples R China.

年份：2022

卷号：40

期号：2

起止页码：401-415

外文期刊名：DRYING TECHNOLOGY

收录：;EI(收录号：20204009260069);Scopus(收录号：2-s2.0-85091690615);WOS:【SCI-EXPANDED(收录号:WOS:000573337600001)】；

语种：英文

外文关键词：Freeze-drying; dehydration rate; sublimation; rehydration capacity; mechanical properties; histological scanning

摘要：Freeze-drying is an effective method for preservation of aortas. In order to maintain the original properties of aortas, the sublimation drying process requires accurate monitoring. In this study, we used a contactless mass measurement device to monitor drying process, porcine aortic segments were divided into four series for freeze-drying, then relevant experiments and calculations were carried out to evaluate the quality of lyophilized samples. The study found that the sublimation process could not be accurately monitored by measured temperature, however, the real-time weighing could do it well, and was suitable to judge the endpoint of primary drying. Meanwhile, the change law of sublimation temperature was obtained by quasi-steady heat transfer equations. The removal ratio of free water during the primary drying greatly affected the properties of lyophilized samples, thorough sublimation had contributed to better performance of products, especially in mechanical properties. In addition, compared with annular aortic segments, the flaky samples had better heat transfer and performed better in histological scanning.