文献类型：期刊文献

中文题名：磺胺胍与四氯苯醌的荷移反应

英文题名：CHARGE-TRANSFERRING REACTION BETWEEN SULFAGUANIDINE AND TETRACHLOROBENZOQUINONE

作者：陈改荣[1];苗郁[1]

第一作者：陈改荣

机构：[1]平原大学化工系

第一机构：新乡学院化学化工学院

年份：2003

卷号：39

期号：9

起止页码：535-536

中文期刊名：理化检验：化学分册

收录：CSTPCD;;北大核心:【北大核心2000】；CSCD:【CSCD_E2011_2012】；

语种：中文

中文关键词：磺胺胍;四氯苯醌;荷移反应;吸光光度法;肠道感染;药物

外文关键词：Photometry; Charge-transferring reaction; Sulfaguanidine; Tetrachlorobenzoquinone

摘要：研究了磺胺胍与四氯苯醌之间的荷移反应。在碳酸钠 碳酸氢钠缓冲溶液中磺胺胍与四氯苯醌能形成淡紫色荷移配合物。配合物的最大吸收波长为540nm,表观摩尔吸光系数为2.45×103L·mol-1·cm-1,线性范围为0～50mg·L-1,其配合比为1∶2。应用拟定的方法测定磺胺胍制剂的含量,平均回收率为99.5%,RSD为0.38%(n=6),可用于实际样品的分析。
It was found that in a Na2CO3NaHCO3 solution buffered in the range of pH 7.7～8.3, a chargetransferring reaction happened between sulfaguanidine (SG) and tetrachlorobenzoquinone (TCBQ) giving a light violetcolored complex (SG∶TCBQ=1∶2) with its absorption maxima at 540nm, and a molar absorptivity of 2.45×103L·mol-1·cm-1. Beer′s law holds, between the absorbance and concentration of SG, in the range of 0～50mg·L-1. A method was devised based on the facts mentioned above, and has been applied to the determination of SG in drug tablets with a RSD (n=6) of 0.38%. The average recovery found was 99.5%.