文献类型：期刊文献

英文题名：A copper iodide-catalyzed coupling reaction of benzofuran-3(2H)-ones with amines: an approach to α-ketoamides

作者：Chen, Rongxiang[1]; Jia, Ruo-Ling[1]; Li, Wenbo[2]; Zhao, Wei[1]; Wang, Kai-Kai[1]; Wang, Zhan-Yong[1]; Ma, Xueji[1]; Dai, Wei[1]; Sun, Aili[1]

第一作者：Chen, Rongxiang

通讯作者：Wang, Kai-Kai

机构：[1] School of Pharmacy, Xinxiang University, Xinxiang, 453000, China; [2] School of Chemistry and Materials Engineering, Xinxiang University, Xinxiang, 453000, China

第一机构：新乡学院

年份：2021

卷号：19

期号：24

起止页码：5294-5297

外文期刊名：Organic and Biomolecular Chemistry

收录：EI(收录号：20212610564763);Scopus(收录号：2-s2.0-85108665483)

基金：We gratefully acknowledge the financial support from the National Natural Science Foundation of China (21702176, 21801214), the Natural Science Foundation of Henan (202300410016) and the funding of the Henan Province University Student Innovation Program (S202011071006).

语种：英文

外文关键词：Amines - Catalysis - Free radicals

摘要：A CuI-catalyzed coupling reaction of benzofuran-3(2H)-ones with amines has been well established for the direct synthesis of α-ketoamides. This process involves C-O bond cleavage and CO/C-N bond formation. Mechanism studies indicated that this α-ketoamide formation reaction may involve a free radical process. ? The Royal Society of Chemistry 2021.