文献类型：期刊文献

英文题名：Synthesis of gamma-Lactones by TBAI-Promoted Intermolecular Carboesterification of Carboxylic Acids with Alkenes and Alcohols

作者：Chen, Rongxiang[1];Wang, Kai-Kai[1];Wang, Zhan-Yong[1];Miao, Changqing[1];Wang, Doudou[1];Zhang, An-an[2];Liu, Lantao[2]

第一作者：Chen, Rongxiang

通讯作者：Chen, RX[1];Liu, LT[2]

机构：[1]Xinxiang Univ, Coll Chem & Chem Engn, Xinxiang 453000, Henan, Peoples R China;[2]Shangqiu Normal Univ, Coll Chem & Chem Engn, Shangqiu 476000, Henan, Peoples R China

第一机构：新乡学院化学化工学院

通讯机构：[1]corresponding author), Xinxiang Univ, Coll Chem & Chem Engn, Xinxiang 453000, Henan, Peoples R China;[2]corresponding author), Shangqiu Normal Univ, Coll Chem & Chem Engn, Shangqiu 476000, Henan, Peoples R China.|[110713]新乡学院化学化工学院;[11071]新乡学院;

年份：2019

卷号：84

期号：24

起止页码：16068-16075

外文期刊名：JOURNAL OF ORGANIC CHEMISTRY

收录：;EI(收录号：20195207916614);Scopus(收录号：2-s2.0-85076823399);WOS:【SCI-EXPANDED(收录号:WOS:000504805700028)，CCR-EXPANDED(收录号:WOS:000504805700028)】；

基金：We gratefully acknowledge financial support from the National Natural Science Foundation of China (21801214, 21572126) and the Higher Education Institution Key Research Project Plan of Henan Province of China (20B150019).

语种：英文

摘要：A novel tetrabutylammonium iodide (TBAI)-promoted three-component reaction of carboxylic acid with alkene and alcohol has been developed, which represents facile and straightforward access to polysubstituted gamma-lactone skeletons in moderate-to-good yields. This methodology is distinguished by the use of a commercial catalyst and readily available starting materials, wide substrate scope, and operational simplicity. Mechanistic studies suggested that this transformation went through a radical process.