成果/Result
- 成纤维细胞生长因子21对1型糖尿病动物模型的肝糖代谢影响及机制研究被引量：21收藏
- 作者：孙国鹏 叶贤龙 任桂萍 李晋南 李德山
- 机构：新乡学院生命科学与技术系;东北农业大学生命科学学院生物制药教研室
- 来源：《生物化学与生物物理进展》 2011
- 关键词：成纤维细胞生长因子21 迟发性1型糖尿病动物模型 糖代谢 胰岛素协同作用 糖尿病治疗药物
- 摘要：成纤维细胞生长因子(FGF)-21是FGF家族的成员之一.作为近年发现的一种新的糖代谢调节因子,大量研究表明,FGF-21是一种不依赖胰岛素,能够独立降糖的2型糖尿病治疗潜力型药物.但是,能否应用于1型糖尿病的治疗,国内...
- Enhancement of the Pharmacological Efficacy of FGF-21 by Genetic Modification and PEGylation被引量：14收藏
- 作者：Ye, Xianlong Qi, Jianying Sun, Guopeng Ren, Guiping Zhu, Shenglong Wu, Yunzhou Yu, Dan Zhao, Jingzhuang Liu, Mingyao Li, Deshan
- 机构：Northeast Agr Univ;Xinxiang Univ;Chinese Acad Fishery Sci;Northeast Agr Univ
- 来源：CURRENT PHARMACEUTICAL BIOTECHNOLOGY 2013
- 关键词：Diabetes FGF-21 genetic modification immunogenicity PEGylation stability
- Up-regulated expression of PD-1 and its ligands during acute Classical Swine Fever virus infection in swine被引量：8收藏
- 作者：Yue, Feng Zhu, Yan-Ping Zhang, Yan-Fang Sun, Guo-Peng Yang, Yuan Guo, Dong-Guang Wang, Ai-Guo Li, Bo-Wen Yin, Mei Cheng, An-Chun Wang, Ming-Shu Wang, Xuan-Nian
- 机构：Xinxiang Univ;Henan Ist Sci & Technol;Sichuan Agr Univ
- 来源：RESEARCH IN VETERINARY SCIENCE 2014
- 关键词：Classical swine fever virus Programmed death-1 Ligand Peripheral blood mononucleur cells Swine
- Overexpression of Programmed Death Ligands in Naturally Occurring Postweaning Multisystemic Wasting Syndrome被引量：7收藏
- 作者：Yue, Feng Cheng, Anchun Zhu, Yanping Li, Peng Zhang, Yanfang Sun, Guopeng Wang, Mingshu Wang, Xuannian
- 机构：Sichuan Agr Univ;Xinxiang Univ
- 来源：VIRAL IMMUNOLOGY 2015
- Prokaryotic expression of the extracellular domain of porcine programmed death 1 (PD-1) and its ligand PD-L1 and identification of the binding with peripheral blood mononuclear cells in vitro被引量：3收藏
- 作者：Zhu, Yan-Ping Yue, Feng He, Yong Li, Peng Yang, Yuan Han, Yu-Ting Zhang, Yan-Fang Sun, Guo-Peng Guo, Dong-Guang Yin, Mei Wang, Xuan-Nian
- 机构：Xinxiang Univ;Henan Inst Sci & Technol
- 来源：CANADIAN JOURNAL OF VETERINARY RESEARCH-REVUE CANADIENNE DE RECHERCHE VETERINAIRE 2017
- Effect of straw enriched environment on behaviors of nursery piglets reared in the farrowing pens被引量：0收藏
- 作者：Yin, Guoan Sun, Guopeng Li, Xiang Liu, Honggui Huang, Dapeng Wei, Chunbo Bao, Jun
- 机构：Heilongjiang Bayi Agr Univ;Xinxiang Univ;Northeast Agr Univ
- 来源：JOURNAL OF ENVIRONMENTAL BIOLOGY 2014
- 关键词：Behavior Nursery pen Piglets Straw
